Article
Deep whole-genome sequencing of 3 cancer cell lines on 2 sequencing platforms.
Scientific reports - 13 Dec 2019
Arora Kanika, Shah Minita, Johnson Molly, Sanghvi Rashesh, Shelton Jennifer, Nagulapalli Kshithija, Oschwald Dayna M, Zody Michael C, Germer Soren, Jobanputra Vaidehi, Carter Jade, Robine Nicolas
Abstract excerpt
To test the performance of a new sequencing platform, develop an updated somatic calling pipeline and establish a reference for future benchmarking experiments, we performed whole-genome sequencing of 3 common cancer cell lines (COLO-829, HCC-1143 and HCC-1187) along with their matched normal cell lines to great sequencing depths (up to 278x coverage) on both Illumina HiSeqX and NovaSeq sequencing instruments....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.