Article
Structural properties of [2Fe-2S] ISCA2-IBA57: a complex of the mitochondrial iron-sulfur cluster assembly machinery.
Scientific reports - 12 Dec 2019
Nasta Veronica, Da Vela Stefano, Gourdoupis Spyridon, Ciofi-Baffoni Simone, Svergun Dmitri I, Banci Lucia
Abstract excerpt
In mitochondria, a complex protein machinery is devoted to the maturation of iron-sulfur cluster proteins. Structural information on the last steps of the machinery, which involve ISCA1, ISCA2 and IBA57 proteins, needs to be acquired in order to define how these proteins cooperate each other. We report here the use of an integrative approach, utilizing information from small-angle X-ray scattering (SAXS) and...
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