Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial Iba57p is required for Fe/S cluster formation on aconitase and activation of radical SAM enzymes.

Molecular and cellular biology - 1 Mar 2008

Gelling Cristy, Dawes Ian W, Richhardt Nadine, Lill Roland, Mühlenhoff Ulrich

Abstract excerpt

A genome-wide screen for Saccharomyces cerevisiae iron-sulfur (Fe/S) cluster assembly mutants identified the gene IBA57. The encoded protein Iba57p is located in the mitochondrial matrix and is essential for mitochondrial DNA maintenance. The growth phenotypes of an iba57Delta mutant and extensiv...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aconitate Hydratase
Share to Enzyme Activation
Share to Iron-Sulfur Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mitochondria

Share to Mitochondrial Proteins

Share to S-Adenosylmethionine

Share to Saccharomyces cerevisiae Proteins

Share to Sulfurtransferases

Source

Open in PubMed Open full text

Identifiers

PMID: 18086897
DOI: 10.1128/MCB.01963-07
PMCID: PMC2258791

Genes

IBA57

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18086897-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial Iba57p is required for Fe/S cluster formation on aconitase and activation of radical SAM enzymes.PMID 18086897Read ↗

A role for tetrahydrofolates in the metabolism of iron-sulfur clusters in all domains of life.Semantic proximity Read ↗

Mutation of the iron-sulfur cluster assembly gene IBA57 causes fatal infantile leukodystrophy.Semantic proximity Read ↗

Iron-sulfur cluster biosynthesis and trafficking - impact on human disease conditions.Semantic proximity Read ↗

CIAO1 loss of function causes a neuromuscular disorder with compromise of nucleocytoplasmic Fe-S enzymesSemantic proximity Read ↗

Mutation of the iron-sulfur cluster assembly gene IBA57 causes severe myopathy and encephalopathy.Semantic proximity Read ↗

The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins.Semantic proximity Read ↗

Mitochondrial iron-sulfur protein biogenesis and human disease.Semantic proximity Read ↗

Iron-sulfur-protein biogenesis in eukaryotes.Semantic proximity Read ↗

Homozygous c.259G>A variant in <i>ISCA1</i> is associated with a new multiple mitochondrial dysfunctions syndromeSemantic proximity Read ↗

Impact of mutations within the [Fe-S] cluster or the lipoic acid biosynthesis pathways on mitochondrial protein expression profiles in fibroblasts from patients.Semantic proximity Read ↗

CIAO1 and MMS19 deficiency: A lethal neurodegenerative phenotype caused by cytosolic Fe-S cluster protein assembly disorders.Semantic proximity Read ↗

Defects in the Maturation of Mitochondrial Iron-Sulfur Proteins: Biophysical Investigation of the MMDS3 Causing Gly104Cys Variant of IBA57.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.