Article
WNT gene polymorphisms and predisposition to apical periodontitis.
Scientific reports - 12 Dec 2019
de Souza Letícia Chaves, Cavalla Franco, Maili Lorena, Garlet Gustavo P, Vieira Alexandre R, Silva Renato M, Letra Ariadne
Abstract excerpt
Single nucleotide polymorphisms (SNPs) in WNT genes may impact gene/protein function and contribute to individual predisposition to apical periodontitis (AP). Here, we investigated the association of SNPs in/nearby WNT3, WNT3A, WNT5A, WNT8A, WNT9B and WNT11 genes with AP using a case-control dataset. Cases were defined as individuals with deep caries and AP (n = 188); controls had deep caries and no AP (n = 230)....
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