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Article

Insights from studies with oral cleft genes suggest associations between WNT-pathway genes and risk of oral cancer.

Journal of dental research - 1 Jun 2011

Andrade Filho P A, Letra A, Cramer A, Prasad J L, Garlet G P, Vieira A R, Ferris R L, Menezes R

Abstract excerpt

Oral squamous cell carcinoma (OSCC) accounts for more than 90% of the malignant neoplasms that arise in the mucosa of the upper aerodigestive tract. Recent studies of cleft lip/palate have shown the association of genes involved in cancer. WNT pathway genes have been associated with several types of cancer and recently with cleft lip/palate. To investigate if genes associated with cleft lip/palate were also...

Topics

Adaptor Proteins, Signal Transducing
Adult
Aged
Aged, 80 and over
Axin Protein
Carcinoma, Squamous Cell
Case-Control Studies
Cleft Lip
Cleft Palate
Female
Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Glycogen Synthase Kinase 3

Glycogen Synthase Kinase 3 beta

Humans

Male

Middle Aged

Mouth Neoplasms

Neoplasm Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 21393552
DOI: 10.1177/0022034511401622
PMCID: PMC3092817

Genes

WNT11
AXIN1
AXIN2
WNT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Insights from studies with oral cleft genes suggest associations between WNT-pathway genes and risk of oral cancer.PMID 21393552Read ↗

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