Article
Insights from studies with oral cleft genes suggest associations between WNT-pathway genes and risk of oral cancer.
Journal of dental research - 1 Jun 2011
Andrade Filho P A, Letra A, Cramer A, Prasad J L, Garlet G P, Vieira A R, Ferris R L, Menezes R
Abstract excerpt
Oral squamous cell carcinoma (OSCC) accounts for more than 90% of the malignant neoplasms that arise in the mucosa of the upper aerodigestive tract. Recent studies of cleft lip/palate have shown the association of genes involved in cancer. WNT pathway genes have been associated with several types of cancer and recently with cleft lip/palate. To investigate if genes associated with cleft lip/palate were also...
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