Article
A permutation method for detecting trend correlations in rare variant association studies.
Genetics research - 13 Dec 2019
Liu Lifeng, Wang Pengfei, Meng Jingbo, Chen Lili, Zhu Wensheng, Ma Weijun
Abstract excerpt
In recent years, there has been an increasing interest in detecting disease-related rare variants in sequencing studies. Numerous studies have shown that common variants can only explain a small proportion of the phenotypic variance for complex diseases. More and more evidence suggests that some of this missing heritability can be explained by rare variants. Considering the importance of rare variants,...
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