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Article

Poisson Approximation-Based Score Test for Detecting Association of Rare Variants.

Annals of human genetics - 1 Jul 2016

Fang Hongyan, Zhang Hong, Yang Yaning

Abstract excerpt

Genome-wide association study (GWAS) has achieved great success in identifying genetic variants, but the nature of GWAS has determined its inherent limitations. Under the common disease rare variants (CDRV) hypothesis, the traditional association analysis methods commonly used in GWAS for common variants do not have enough power for detecting rare variants with a limited sample size. As a solution to this...

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PMID: 27346734
DOI: 10.1111/ahg.12154

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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