Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation in IL28B is associated with the development of hepatitis B-related hepatocellular carcinoma.

Cancer immunology, immunotherapy : CII - 1 Sept 2012

Ren Shan, Lu Junfeng, Du Xiaofei, Huang Yanxiang, Ma Lina, Huo Honglei, Chen Xinyue, Wei Lai

Abstract excerpt

To evaluate the role of host IL28B (interleukin 28B; interferon lambda 3) single nucleotide polymorphisms (SNPs) in predicting hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) susceptibility, three SNPs in the IL28B gene (rs12979860C/T, rs8099917G/T and rs12980275G/A) were examined in 330 subjects (including 154 HBV-related HCC patients, 86 non-HCC patients with chronic hepatitis B (CHB), 43 HBV...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Hepatitis B, Chronic

Share to Interferons

Share to Interleukins

Share to Liver Neoplasms

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 22310928
DOI: 10.1007/s00262-012-1203-y
PMCID: PMC11029740

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation in IL28B is associated with the development of hepatitis B-related hepatocellular carcinoma.PMID 22310928Read ↗

The influence of interleukin 28B polymorphisms on the risk of hepatocellular carcinoma among patients with HBV or HCV infectionSemantic proximity Read ↗

Influence of interleukin-28B polymorphism on progression to hepatitis virus-induced hepatocellular carcinoma.Semantic proximity Read ↗

Gene polymorphisms of interleukin 28B and the risk to chronic hepatitis B virus infection in Thai.Semantic proximity Read ↗

Association of the interleukin-28B gene polymorphism with development of hepatitis virus-related hepatocellular carcinoma and liver cirrhosis: a meta-analysis.Semantic proximity Read ↗

The role of interleukin 28B gene polymorphism in Turkish patients with hepatocellular carcinoma.Semantic proximity Read ↗

A meta-analysis of the association between IL28B polymorphisms and infection susceptibility of hepatitis B virus in Asian population.Semantic proximity Read ↗

Expression and gene polymorphisms of interleukin 28B and hepatitis B virus infection in a Chinese Han population.Semantic proximity Read ↗

IL-28B rs12979860 polymorphism affect the course of chronic hepatitis and the development of HCC in Egyptian patients with hepatitis C type 4.Semantic proximity Read ↗

Association of polymorphisms in interleukin-18 and interleukin-28B genes with outcomes of hepatitis B virus infections: a meta-analysis.Semantic proximity Read ↗

Association analysis between SNPs in IL-28B gene and the progress of hepatitis B infection in Han Chinese.Semantic proximity Read ↗

Association of IL28B gene polymorphism with development of hepatocellular carcinoma in Japanese patients with chronic hepatitis C virus infection.Semantic proximity Read ↗

Impact of IL28B genetic variation on HCV-induced liver fibrosis, inflammation, and steatosis: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.