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Stage-resolved metabolomics reveals the methionine cycle as a key regulator of <i>Aedes aegypti</i> development and dengue virus susceptibility

2025-12-29

Abstract excerpt

<h4>SUMMARY</h4> Developmental transitions in the mosquito Aedes aegypti are central to vector competence and disease transmission, yet the underlying metabolic programs remain poorly defined. Here, we use untargeted metabolomics, gene expression analysis, and functional assays to delineate stage-specific metabolic fingerprints across the mosquito life cycle, from egg and larva to pupa and adult. Our profiling o...

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Literature Corpus work
e7e67ec3-6b0c-57da-bd6c-4891360c4999
DOI
10.64898/2025.12.29.696135
Open publication

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Stage-resolved metabolomics reveals the methionine cycle as a key regulator of <i>Aedes aegypti</i> development and dengue virus susceptibilityDOI 10.64898/2025.12.29.696135
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