Article
[Importance of next generation sequencing in precision oncology approach of acute myeloid leukemia].
Magyar onkologia - 9 Dec 2019
Andrikovics Hajnalka, Kövy Petra, Bors András, Csabán Dóra, Meggyesi Nóra, Õrfi Zoltán, Borsy Adrienn, Kozma András, Dolgos János, Harasztdombi József, Mikala Gábor, Reményi Péter, Vályi-Nagy István
Abstract excerpt
In contrast to solid tumours, the genetic background of acute myeloid leukemia (AML) is characterized by a relatively low number of alterations per sample (average 3-5 mutations similarly to paediatric malignancies). Although the mutational background is rather heterogeneous, the detection of genetic alterations has diagnostic, prognostic and therapeutic relevance. We investigated cytogenetic and most commonly...
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