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Article

DAXX mutations as potential genomic markers of malignant evolution in small nonfunctioning pancreatic neuroendocrine tumors.

Scientific reports - 9 Dec 2019

Cives Mauro, Partelli Stefano, Palmirotta Raffaele, Lovero Domenica, Mandriani Barbara, Quaresmini Davide, Pelle' Eleonora, Andreasi Valentina, Castelli Paola, Strosberg Jonathan, Zamboni Giuseppe, Falconi Massimo, Silvestris Franco

Abstract excerpt

Management of localized well-differentiated pancreatic neuroendocrine tumors (panNETs) is controversial and primarily dependent on tumor size. Upfront surgery is usually recommended for tumors larger than 2 cm in diameter since they frequently show metastatic potential, whereas smaller panNETs are generally characterized by an indolent clinical course, with a rate of relapse or metastasis below 15%. To explore...

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Identifiers

PMID: 31819132
DOI: 10.1038/s41598-019-55156-0
PMCID: PMC6901561

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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