The Impact of Genetic Variations in ADORA2A in the Association between Caffeine Consumption and Sleep.

doi:10.3390/genes10121021

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

The Impact of Genetic Variations in ADORA2A in the Association between Caffeine Consumption and Sleep.

Genes - 6 Dec 2019

Erblang Mégane, Drogou Catherine, Gomez-Merino Danielle, Metlaine Arnaud, Boland Anne, Deleuze Jean François, Thomas Claire, Sauvet Fabien, Chennaoui Mounir

Abstract excerpt

ADORA2A has been shown to be responsible for the wakefulness-promoting effect of caffeine and the 1976T>C genotype (SNP rs5751876, formerly 1083T>C) to contribute to individual sensitivity to caffeine effects on sleep. We investigate the association between six single nucleotide polymorphisms (SNP) from ADORA2A and self-reported sleep characteristics and caffeine consumption in 1023 active workers of European...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alleles

Share to Caffeine

Share to Linkage Disequilibrium

Share to Polymorphism, Single Nucleotide

Share to Receptor, Adenosine A2A

Share to Sleep

Share to Sleep Initiation and Maintenance Disorders

Source

Open in PubMed Open full text

Identifiers

PMID: 31817803
DOI: 10.3390/genes10121021
PMCID: PMC6947650

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Impact of Genetic Variations in ADORA2A in the Association between Caffeine Consumption and Sleep.PMID 31817803Read ↗

A genetic variation in the adenosine A2A receptor gene (ADORA2A) contributes to individual sensitivity to caffeine effects on sleep.Semantic proximity Read ↗

The association between caffeine consumption and objective sleep variables is dependent on ADORA2A c.1083T>C genotypes.Semantic proximity Read ↗

"No thanks, coffee keeps me awake": individual caffeine sensitivity depends on ADORA2A genotype.Semantic proximity Read ↗

Caffeine consumption and behavioral symptoms: influence of ADORA2A and DRD2 genes on inattention.Semantic proximity Read ↗

Association of the anxiogenic and alerting effects of caffeine with ADORA2A and ADORA1 polymorphisms and habitual level of caffeine consumption.Semantic proximity Read ↗

Coffee, ADORA2A, and CYP1A2: the caffeine connection in Parkinson's disease.Semantic proximity Read ↗

Coffee effectively attenuates impaired attention in ADORA2A C/C-allele carriers during chronic sleep restriction.Semantic proximity Read ↗

Effects of the adenosine deaminase polymorphism and caffeine intake on sleep parameters in a large population sample.Semantic proximity Read ↗

The effect of caffeine on cognitive performance is influenced by CYP1A2 but not ADORA2A genotype, yet neither genotype affects exercise performance in healthy adults.Semantic proximity Read ↗

A genome-wide association study of caffeine-related sleep disturbance: confirmation of a role for a common variant in the adenosine receptor.Semantic proximity Read ↗

Modeling caffeine concentrations with the Stanford Caffeine Questionnaire: preliminary evidence for an interaction of chronotype with the effects of caffeine on sleep.Semantic proximity Read ↗

Sleep Quality and Duration in Children That Consume Caffeine: Impact of Dose and Genetic Variation in ADORA2A and CYP1A.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.