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Article

Targeting RAS in pediatric cancer: is it becoming a reality?

Current opinion in pediatrics - 1 Feb 2020

Vaseva Angelina V, Yohe Marielle E

Abstract excerpt

PURPOSE OF REVIEW: The current review aims to highlight the frequency of RAS mutations in pediatric leukemias and solid tumors and to propose strategies for targeting oncogenic RAS in pediatric cancers. RECENT FINDINGS: The three RAS genes (HRAS, NRAS, and KRAS) comprise the most frequently mutated oncogene family in human cancer. RAS mutations are commonly observed in three of the leading causes of cancer death...

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Identifiers

PMID: 31815779
DOI: 10.1097/MOP.0000000000000856
PMCID: PMC9422199

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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