Article
Identifying Mutually Exclusive Gene Sets with Prognostic Value and Novel Potential Driver Genes in Patients with Glioblastoma.
BioMed research international - 1 Jan 2019
Gao Qian, Cui Yan, Shen Yanan, Li Yanyan, Gao Xue, Xi Yanfeng, Wang Tong
Abstract excerpt
The pathogenesis and prognosis of glioblastoma (GBM) remain poorly understood. Mutual exclusivity analysis can distinguish driver genes and pathways from passenger ones. The purpose of this study was to identify mutually exclusive gene sets (MEGSs) that have prognostic value and to detect novel driver genes in GBM. The genomic alteration profile and clinical information were derived from The Cancer Genome Atlas,...
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