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Analysis of the EGFR Amplification and CDKN2A Deletion Regulated Transcriptomic Signatures Reveals the Prognostic Significance of SPATS2L in Patients With Glioma

20 Apr 2021

Abstract excerpt

Purpose: This study was conducted in order to analyze the prognostic effects of epidermal growth factor receptor (EGFR) and CDKN2A alterations and determine the prognostic significance of EGFR and CDKN2A alterations on regulated genes in patients with glioblastoma (GBM) or lower grade glioma (LGG). Methods: The alteration frequencies of EGFR and CDKN2A across 32 tumor types were derived from cBioPortal based on...

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PMID: 33959491
DOI: 10.3389/fonc.2021.551160

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