Article
Association of genetic polymorphisms in chromosome 9p21 with risk of ischemic stroke.
Cytokine - 1 Mar 2020
Han Xuemei, Wang Chunhui, Tang Dong, Shi Yuqing, Gao Ming
Abstract excerpt
Genome-wide association study (GWAS) has identified that rs10757278 in chromosome 9p21 was a risk loci of ischemic stroke (IS). Interferon-beta 1 (IFNB1), located on 9p21, has a protective role in IS. In this study, we aimed to investigate whether the rs10757278, rs9333358 and rs1051922 in IFNB1 were related to the risk of IS. The 3 polymorphisms were genotyped using a TaqMan allelic discrimination assay in 505...
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