Article
T Allele of nonsense polymorphism (rs2039381, Gln71Stop) of interferon-ε is a risk factor for the development of intracerebral hemorrhage.
Human immunology - 1 Jan 2014
Kim Su Kang, Park Hae Jeong, Kim Jong Woo, Chung Joo-Ho, Yoo Seung Don, Kim Dong Hwan, Yun Dong Hwan, Kim Hee-Sang
Abstract excerpt
Interferons (IFNs) play key roles in various biologic responses including antiviral and immune reactions. We evaluated one possible risk factor in nonsense polymorphism (rs2039381, Gln71Stop) of interferon-ε (IFNE). We recruited stroke [119 ischemic stroke (IS) and 145 intracerebral hemorrhage (ICH)] and control (401), respectively. The nonsense SNP (rs2039381, Gln71Stop) of IFNE was selected. We identified...
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