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Article

Molecular dynamics and computational study of Mannich-based coumarin derivatives: potent tyrosine kinase inhibitor

6 Dec 2019

Abstract excerpt

The manifestation of bacterial UTI (Urinary Tract Infection) has been predominantly endemic, globally; eventually, the development of new UTI antibacterial agent(s) remains the call of the day. Herein, two series of Mannich-based 4-hydroxy coumarin derivatives, 7a-m and 8a-m were designed by suitable heterocyclic amines condensed with aldehydes. The synthesised molecules were interpreted by 1H-NMR and 13C-NMR...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 31809673
DOI: 10.1080/07391102.2019.1701554

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