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Coumarin‐containing hybrids and their antibacterial activities

6 Apr 2020

Abstract excerpt

Infections caused by Gram-positive and -negative bacteria are one of the foremost causes of morbidity and mortality globally. Antibiotics are the mainstay of therapy for bacterial infections, but the emergence and wide spread of drug-resistant pathogens have already become a huge issue for public healthcare systems. The coumarin moiety, which is ubiquitous in nature, could bind to the B subunit of DNA gyrase in...

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PMID: 32253782
DOI: 10.1002/ardp.201900380

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