Article
Molecular analysis of adrenergic receptor genes and interleukin-4/interleukin-4 receptor genes in patients with interstitial cystitis.
The Journal of urology - 1 Dec 2002
Sugaya Kimio, Nishijima Saori, Yamada Tetsuo, Miyazato Minoru, Hatano Tadashi, Ogawa Yoshihide
Abstract excerpt
PURPOSE: Interstitial cystitis is a chronic and sterile inflammatory disease of the bladder. Clinically many patients with interstitial cystitis also have allergic or autoimmune diseases. Recent studies have suggested that allelic variations in the adrenergic receptor beta2 gene, the interleukin (IL)-4 gene and its receptor gene are closely associated with immune diseases. Therefore, we studied adrenergic...
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