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Article

Induction of Kaposi's Sarcoma-Associated Herpesvirus-Encoded Thymidine Kinase (ORF21) by X-Box Binding Protein 1.

Journal of virology - 14 Feb 2020

Wang Victoria, Davis David A, Deleage Claire, Brands Catherine, Choi Hong S, Haque Muzammel, Yarchoan Robert

Abstract excerpt

Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent for Kaposi sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman disease (MCD). Like other herpesviruses, it has latent and lytic repertoires. However, there is evidence that some lytic genes can be directly activated by certain cellular factors. Cells undergoing endoplasmic reticulum stress express spliced X-box binding...

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Share to Gene Expression Regulation, Viral
Share to Herpesvirus 8, Human

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Sarcoma, Kaposi

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Source

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Identifiers

PMID: 31801863
DOI: 10.1128/JVI.01555-19
PMCID: PMC7022350

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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