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Article

B cell terminal differentiation factor XBP‐1 induces reactivation of Kaposi's sarcoma‐associated herpesvirus

29 Jun 2007

Abstract excerpt

The herpesvirus life cycle has two distinct phases: latency and lytic replication. The viral immediate early protein replication and transcription activator (RTA) plays a central role in mediating the balance between these two phases. Here, we demonstrate that a B cell terminal differentiation factor X-box binding protein 1 (XBP-1) can effectively initiates Kaposi's sarcoma-associated herpesvirus (KSHV)...

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PMID: 17617410
DOI: 10.1016/j.febslet.2007.06.056

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