Graph-based information diffusion method for prioritizing functionally related genes in protein-protein interaction networks.

Abstract excerpt

Shortest path length methods are routinely used to validate whether genes of interest are functionally related to each other based on biological network information. However, the methods are computationally intensive, impeding extensive utilization of network information. In addition, non-weighted shortest path length approach, which is more frequently used, often treat all network connections equally without...

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