Article
The potential impact of tumor suppressor genes on human gametogenesis: a case-control study.
Journal of assisted reproduction and genetics - 1 Feb 2020
Hershlag Avner, Peyser Alexandra, Bristow Sara L, Puig Oscar, Pollock Andrew, Niknazar Mohamad, Mills Alea A
Abstract excerpt
PURPOSE: To study the incidence of tumor suppressor gene (TSG) mutations in men and women with impaired gametogenesis. METHODS: Gene association analyses were performed on blood samples in two distinct patient populations: males with idiopathic male infertility and females with unexplained diminished ovarian reserve (DOR). The male study group consisted of men with idiopathic azoospermia, oligozoospermia,...
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