Article
Monoamine transporter gene polymorphisms affect susceptibility to depression and predict antidepressant response.
Psychopharmacology - 1 Aug 2009
Min Wenjiao, Li Tao, Ma Xiaohong, Li Zhengyu, Yu Tao, Gao Dong, Zhang Bo, Yun Yang, Sun Xueli
Abstract excerpt
RATIONALE: Serotonin transporter (5-HTT) and norepinephrine transporter (NET) are the primary targets of many antidepressants. We aimed to determine the potential correlations of 5-HTT/NET gene polymorphisms with the susceptibility to depression and the antidepressant response to selective serotonin reuptake inhibitors (SSRIs) or dual selective serotonin/norepinephrine reuptake inhibitors (SNRIs). METHODS: A...
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