Article
COL5A1 rs12722 polymorphism is not associated with passive muscle stiffness and sports-related muscle injury in Japanese athletes.
BMC medical genetics - 2 Dec 2019
Miyamoto-Mikami Eri, Miyamoto Naokazu, Kumagai Hiroshi, Hirata Kosuke, Kikuchi Naoki, Zempo Hirofumi, Kimura Noriko, Kamiya Nobuhiro, Kanehisa Hiroaki, Naito Hisashi, Fuku Noriyuki
Abstract excerpt
BACKGROUND: Poor joint flexibility has been repeatedly proposed as a risk factor for muscle injury. The C-to-T polymorphism (rs12722) in the 3'-untranslated region of the collagen type V α1 chain gene (COL5A1) is reportedly associated with joint flexibility. Flexibility of a normal joint is largely determined by passive muscle stiffness, which is influenced by intramuscular collagenous connective tissues...
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