Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Female Athletes Genetically Susceptible to Fatigue Fracture Are Resistant to Muscle Injury: Potential Role of COL1A1 Variant.

Medicine and science in sports and exercise - 1 Sept 2021

Miyamoto-Mikami Eri, Kumagai Hiroshi, Tanisawa Kumpei, Taga Yuki, Hirata Kosuke, Kikuchi Naoki, Kamiya Nobuhiro, Kawakami Ryoko, Midorikawa Taishi, Kawamura Takuji, Kakigi Ryo, Natsume Toshiharu, Zempo Hirofumi, Suzuki Koya, Kohmura Yoshimitsu, Mizuno Kazunori, Torii Suguru, Sakamoto Shizuo, Oka Koichiro, Higuchi Mitsuru, Naito Hisashi, Miyamoto Naokazu, Fuku Noriyuki

Abstract excerpt

PURPOSE: We aimed to investigate the hypothesis that type I collagen plays a role in increasing bone mineral density (BMD) and muscle stiffness, leading to low and high risks of fatigue fracture and muscle injury, respectively, in athletes. As a potential mechanism, we focused on the effect of the type I collagen alpha 1 chain gene (COL1A1) variant associated with transcriptional activity on bone and skeletal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Collagen Type I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Muscle, Skeletal

Share to Polymorphism, Genetic

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 33731655
DOI: 10.1249/MSS.0000000000002658
PMCID: PMC8360671

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Female Athletes Genetically Susceptible to Fatigue Fracture Are Resistant to Muscle Injury: Potential Role of COL1A1 Variant.PMID 33731655Read ↗

Interactions between Gene Variants within the COL1A1 and COL5A1 Genes and Musculoskeletal Injuries in Physically Active Caucasian.Semantic proximity Read ↗

eQTL variants in COL22A1 are associated with muscle injury in athletes.Semantic proximity Read ↗

Biological variation in musculoskeletal injuries: current knowledge, future research and practical implications.Semantic proximity Read ↗

Variations of collagen-encoding genes are associated with exercise-induced muscle damage.Semantic proximity Read ↗

Association of polymorphisms rs1800012 in COL1A1 with sports-related tendon and ligament injuries: a meta-analysis.Semantic proximity Read ↗

Effects of Exercise Addiction and the COL1A1 Gene rs1800012 Polymorphism on Injury Susceptibility in Elite Female Volleyball Players.Semantic proximity Read ↗

Collagen Gene Polymorphisms Previously Associated with Resistance to Soft-Tissue Injury Are More Common in Competitive Runners Than Nonathletes.Semantic proximity Read ↗

Influence of type I collagen polymorphisms and risk of anterior cruciate ligament rupture in athletes: a case-control study.Semantic proximity Read ↗

Genetic Variations in Susceptibility to Traumatic Muscle Injuries and Muscle Pain among Brazilian High-Performance Athletes.Semantic proximity Read ↗

The Role of COL1A1, COL5A1, ACTN3, MMP3, and GDF5 Gene Variants in Common Sports Injuries: Systematic Review of ACL Rupture, Achilles Tendinopathy, and Stress Fractures.Semantic proximity Read ↗

Association Between COL5a1, COL11a1, and COL11a2 Gene Variations and Rotator Cuff Tendinopathy in Young Athletes.Semantic proximity Read ↗

COL11A1 gene is associated with limbus vertebra in gymnasts.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.