Article
Polymorphisms at the PRNP gene influence susceptibility to chronic wasting disease in two species of deer (Odocoileus Spp.) in western Canada.
Journal of toxicology and environmental health. Part A - 1 Jan 2009
Wilson Gregory A, Nakada Stephanie M, Bollinger Trent K, Pybus Margo J, Merrill Evelyn H, Coltman David W
Abstract excerpt
Chronic wasting disease (CWD) is increasingly prevalent in multiple wild mule (Odocoileus hemionus) and white-tailed deer (O. virginianus) herds in North America. CWD was first found in Canadian wild mule deer in Saskatchewan in 2000 and has since spread into the neighboring province of Alberta. The infectious agent for CWD is a misfolded prion protein encoded by the PRNP gene. Previous studies revealed...
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