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Article

Base excision repair but not DNA double‐strand break repair is impaired in aged human adipose‐derived stem cells

29 Nov 2019

Abstract excerpt

The decline in DNA repair capacity contributes to the age-associated decrease in genome integrity in somatic cells of different species. However, due to the lack of clinical samples and appropriate tools for studying DNA repair, whether and how age-associated changes in DNA repair result in a loss of genome integrity of human adult stem cells remains incompletely characterized. Here, we isolated 20 eyelid...

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PMID: 31782607
DOI: 10.1111/acel.13062

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