Article
Berberine ameliorates cellular senescence and extends the lifespan of mice via regulating p16 and cyclin protein expression
26 Nov 2019
Abstract excerpt
Abstract Although aging and senescence have been extensively studied in the past few decades, however, there is lack of clinical treatment available for anti‐aging. This study presents the effects of berberine (BBR) on the aging process resulting in a promising extension of lifespan in model organisms. BBR extended the replicative lifespan, improved the morphology, and boosted rejuvenation markers of replicative...
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