Article
High Nuclease Activity of Long Persisting Staphylococcus aureus Isolates Within the Airways of Cystic Fibrosis Patients Protects Against NET-Mediated Killing
5 Nov 2019
Abstract excerpt
Staphylococcus aureus is one of the first and one of the most prevalent pathogens cultured from the airways of cystic fibrosis (CF) patients, which can persist therefor extended periods. Airway infections in CF patients are characterized by a strong inflammatory response of highly recruited neutrophils. One killing mechanism of neutrophils is the formation of neutrophil extracellular traps (NETs), which capture...
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