Article
The staphylococcal nuclease prevents biofilm formation in Staphylococcus aureus and other biofilm-forming bacteria.
Science China. Life sciences - 1 Sept 2011
Tang Junni, Kang Mingsong, Chen Huanchun, Shi Xianming, Zhou Rui, Chen Juan, Du Yiwu
Abstract excerpt
The staphylococcal nuclease, encoded by the nuc1 gene, is an important virulence factor of Staphylococcus aureus. However, the physiological role of the nuclease has not been fully characterized. The current study observed that biofilm development could be prevented in staphylococcal nuclease-producing strains of S. aureus; however, when the nuc1 gene was knocked out, the ability to form a biofilm significantly...
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