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Article

X-chromosome genetic association test incorporating X-chromosome inactivation and imprinting effects.

Journal of genetics - 1 Nov 2019

Liu Wei, Wang Bei-Qi, Liu-Fu Guojun, Fung Wing Kam, Zhou Ji-Yuan

Abstract excerpt

Studies have shown that many complex diseases are sex-determined. When conducting genetic association studies on X-chromosome, there are two important epigenetic factors which should be considered simultaneously: X-chromosome inactivation and genomic imprinting. Currently, there have been several association tests accounting for the information on X-chromosome inactivation. However, these tests do not take the...

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PMID: 31767819

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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