Article
Powerful tests for association on quantitative trait loci incorporating imprinting effects.
Journal of human genetics - 1 Jun 2013
Xia Fan, Zhou Ji-Yuan, Fung Wing Kam
Abstract excerpt
Genomic imprinting is an important epigenetic factor in complex traits study, and there has recently been considerable interest in association study for quantitative traits by incorporating imprinting. However, these methods need the assumptions of Hardy-Weinberg equilibrium or only use information from families with one child. In this paper, by taking imprinting into account and making no assumption about the...
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