Article
Construction of a multicopy genomic DNA library and its application for suppression analysis.
Journal of microbiology (Seoul, Korea) - 1 Dec 2019
Cho Hongbaek
Abstract excerpt
Suppression analysis is used for the identification of new genes and genetic interactions when there is a notable phenotype available for genetic selection or screening. A random genomic DNA library constructed on a multi-copy plasmid is a useful tool for suppression analysis when one expects that an overdose of a few genes will suppress the phenotype. These libraries have been successfully used to determine the...
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