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Article

Genomic analysis uncovers a phenotypically diverse but genetically homogeneous Escherichia coli ST131 clone circulating in unrelated urinary tract infections.

The Journal of antimicrobial chemotherapy - 1 Apr 2012

Clark Gemma, Paszkiewicz Konrad, Hale James, Weston Vivienne, Constantinidou Chrystala, Penn Charles, Achtman Mark, McNally Alan

Abstract excerpt

OBJECTIVES: To determine variation at the genome level in Escherichia coli ST131 clinical isolates previously shown to be phenotypically diverse. METHODS: The genomes of 10 ST131 isolates extensively characterized in previous studies were sequenced using combinations of Illumina and 454 sequencing technology. Whole-genome comparisons and phylogenetic comparisons were then performed across the strain set and with...

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PMID: 22258927
DOI: 10.1093/jac/dkr585

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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