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Article

Integrative Clinical Sequencing in the Management of Refractory or Relapsed Cancer in Youth

1 Sept 2015

Abstract excerpt

IMPORTANCE: Cancer is caused by a diverse array of somatic and germline genomic aberrations. Advances in genomic sequencing technologies have improved the ability to detect these molecular aberrations with greater sensitivity. However, integrating them into clinical management in an individualized manner has proven challenging. OBJECTIVE: To evaluate the use of integrative clinical sequencing and genetic...

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PMID: 26325560
DOI: 10.1001/jama.2015.10080

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