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Article

Molecular diagnostics enables detection of actionable targets: the Pediatric Targeted Therapy 2.0 registry.

European journal of cancer (Oxford, England : 1990) - 1 Feb 2023

Ecker Jonas, Selt Florian, Sturm Dominik, Sill Martin, Korshunov Andrey, Hirsch Steffen, Capper David, Dikow Nicola, Sutter Christian, Müller Carina, Sigaud Romain, Eggert Angelika, Simon Thorsten, Niehues Tim, von Deimling Andreas, Pajtler Kristian W, van Tilburg Cornelis M, Jones David T W, Sahm Felix, Pfister Stefan M, Witt Olaf, Milde Till

Abstract excerpt

BACKGROUND: Precision oncology requires diagnostic accuracy and robust detection of actionable alterations. The Pediatric Targeted Therapy (PTT) 2.0 program aims at improving diagnostic accuracy by addition of molecular analyses to the existing histological diagnosis and detection of actionable alterations for relapsed paediatric oncology patients, in cases with limited availability of tumour material. METHODS:...

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PMID: 36542877
DOI: 10.1016/j.ejca.2022.11.015

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