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Tandem amplification of the vanM gene cluster drives vancomycin resistance in vancomycin-variable enterococci

20 Oct 2019

Abstract excerpt

BACKGROUND: Vancomycin-variable enterococci (VVE) are a potential risk factor for vancomycin resistance gene dissemination and clinical treatment failure. vanM has emerged as a new prevalent resistance determinant among clinical enterococci in China. A total of 54 vancomycin-susceptible enterococci (VSE) isolates carrying incomplete vanM gene clusters were isolated in our previous study. OBJECTIVES: To determine...

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PMID: 31742612
DOI: 10.1093/jac/dkz461

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