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Article

Vancomycin variable Enterococci in the Netherlands (2018-2023) and the mechanism of resistance induction.

PloS one - 1 Jan 2026

von Wintersdorff Christian J H, Roelofsen Milika, Versteegh Linda, Benyahya Yassin, Jamin Casper, Mulder Marlies, Bastiaens Guido J H, van Meer Maurits P A, Flipse Jacky

Abstract excerpt

Enterococci are common human commensals but can cause severe infections in immunocompromised patients. Enterococcus faecium is a notable example, capable of acquiring resistance to multiple antibiotics, including the critically important drug vancomycin. Such strains, known as vancomycin-resistant E. faecium (VRE), are routinely detected in clinical laboratories using phenotypic assays. However, some isolates...

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Identifiers

PMID: 41650167
DOI: 10.1371/journal.pone.0342092
PMCID: PMC12880688

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