Article
Elucidating vancomycin-resistant Enterococcus faecium outbreaks: the role of clonal spread and movement of mobile genetic elements.
The Journal of antimicrobial chemotherapy - 1 Dec 2018
Zhou X, Chlebowicz M A, Bathoorn E, Rosema S, Couto N, Lokate M, Arends J P, Friedrich A W, Rossen J W A
Abstract excerpt
Background: Vancomycin-resistant Enterococcus faecium (VREfm) has emerged as a nosocomial pathogen worldwide. The dissemination of VREfm is due to both clonal spread and spread of mobile genetic elements (MGEs) such as transposons. Objectives: We aimed to combine vanB-carrying transposon data with core-genome MLST (cgMLST) typing and epidemiological data to understand the pathways of transmission in nosocomial...
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