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Article

Pivotal role of interleukin 27 serum level and missense variant (rs181206) in multiple sclerosis.

Journal of immunoassay & immunochemistry - 1 Jan 2026

Elashkar Amany E, Khalil Marwa M, Elkholy Mona S, Samy Eman, Hamam Sanaa S, Elmaghraby Amira Samy

Abstract excerpt

The incidence of multiple sclerosis (MS) has increased in recent years. Its pathogenesis involves the interaction between various elements, with interleukin 27 (IL-27) playing a key role in autoimmunity. The presence of the IL-27 receptor on astrocytes emphasizes its involvement in the disease's progression. PURPOSE: The study aims to investigate possible associations between IL27 rs181206, serum level of IL27,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41636368
DOI: 10.1080/15321819.2026.2623279

Genes

IL27

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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