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Article

In search of the next super models.

EMBO molecular medicine - 1 Dec 2019

Goedel Alexander, Grote Beverborg Niels, Sahara Makoto, Chien Kenneth R

Abstract excerpt

The advent of pluripotent stem cell biology and facile genetic manipulation via CRISPR technology has ushered in a new era of human disease models for drug discovery and development. While these precision "super models" hold great promise for tailoring personalized therapy, their full potential and in vivo validation have remained elusive.

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Identifiers

PMID: 31736275
DOI: 10.15252/emmm.201911502
PMCID: PMC6895600

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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