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Article

Hepatotoxicity during TB treatment in people with HIV/AIDS related to NAT2 polymorphisms in Pernambuco, Northeast Brazil.

Annals of hepatology - 1 Jan 2000

Araujo-Mariz Carolline, Militão de Albuquerque Maria de Fátima P, Lopes Edmundo P, Ximenes Ricardo A A, Lacerda Heloísa R, Miranda-Filho Demócrito B, Lustosa-Martins Brena B, Pastor André Filipe P, Acioli-Santos Bartolomeu

Abstract excerpt

INTRODUCTION AND OBJECTIVE: Hepatotoxicity during tuberculosis (TB) treatment is frequent and may be related to the Arylamine N-Acetyltransferase (NAT2) acetylator profile, in which allele frequencies differ according to the population. The aim of this study was to investigate functional polymorphisms in NAT2 associated with the development of hepatotoxicity after initiating treatment for TB in people living with...

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Identifiers

PMID: 31734174
DOI: 10.1016/j.aohep.2019.09.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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