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Article

Association of TAP 1 and 2 gene polymorphisms with human immunodeficiency virus-tuberculosis co-infection.

Human immunology - 1 Oct 2011

Sunder Sharada Ramaseri, Hanumanth Surekha Rani, Gaddam Sumanlatha, Jonnalagada Subbanna, Valluri Vijaya Lakshmi

Abstract excerpt

Major histocompatibility complex (MHC) class I binding peptides are carried from cytosol to the lumen of the endoplasmic reticulum (ER) by transporter associated with antigen processing (TAP), an integral ER membrane protein composed of two subunits, TAP1 and TAP2. Polymorphism in TAP genes may influence these proteins further affecting the antigen peptide presentation, indirectly resulting in the viral escape...

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Share to ATP Binding Cassette Transporter, Subfamily B, Member 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21843574
DOI: 10.1016/j.humimm.2011.07.304

Genes

TAP1
TAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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