Article
Relationship of COL9A1 and SOX9 Genes with Genetic Susceptibility of Postmenopausal Osteoporosis.
Calcified tissue international - 1 Mar 2020
Liu Hongliang, Zhao Hongmou, Lin Hua, Li Zhong, Xue Hanzhong, Zhang Yunzhi, Lu Jun
Abstract excerpt
As one of the most common types of osteoporosis, postmenopausal osteoporosis (PMOP) is caused by both genetic and environmental factors. Previous studies have indicated that SOX9 activity is tightly regulated to ensure normal bone mineral density (BMD) in the adult skeleton, and the COL9A1 promoter region can be transactivated by SOX9. In this study, we aimed to investigate the potential association between PMOP...
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