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Article

TMEM16A chloride channel does not drive mucus production

15 Nov 2019

Abstract excerpt

channels such as TMEM16A can likely compensate for defective CFTR. However, TMEM16A was recently described as a key driver in mucus production/secretion. Here, we have examined whether indeed there is a causal relationship between TMEM16A and MUC5AC production, the main component of respiratory mucus. Our data show that TMEM16A and MUC5AC are inversely correlated during differentiation of human airway cells....

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Identifiers

PMID: 31732694
DOI: 10.26508/lsa.201900462

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