Article
Investigating the mechanisms of papillary thyroid carcinoma using transcriptome analysis.
Molecular medicine reports - 1 Nov 2017
Qiu Jie, Zhang Wenwei, Xia Qingsheng, Liu Fuxue, Zhao Shuwei, Zhang Kailing, Chen Min, Zang Chuanshan, Ge Ruifeng, Liang Dapeng, Sun Yan
Abstract excerpt
As the predominant thyroid cancer, papillary thyroid cancer (PTC) accounts for 75‑85% of thyroid cancer cases. This research aimed to investigate transcriptomic changes and key genes in PTC. Using RNA‑sequencing technology, the transcriptional profiles of 5 thyroid tumor tissues and 5 adjacent normal tissues were obtained. The single nucleotide polymorphisms (SNPs) were identified by SAMtools software and then...
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