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Article

Comparative genomics and molecular insights into smooth and rough clinical isolates of Mycobacterium abscessus.

Microbial genomics - 1 May 2026

Kumar Rajender, Braian Clara, Fröberg Gabrielle, Forsman Lina Davies, Schön Thomas

Abstract excerpt

Background. Our recent findings indicate that the rough form of the Mycobacterium abscessus complex (MABC) is associated with worse clinical outcomes compared to the smooth variant. The glycopeptidolipid (GPL) locus has been considered vital for this transition; however, this has only been shown during in vitro selection. Thus, we aimed to investigate genetic differences between the morphotypes among clinical...

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Identifiers

PMID: 42089874
DOI: 10.1099/mgen.0.001687
PMCID: PMC13158036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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