Article
An Explorative Study of CYP2D6's Polymorphism in a Sample of Chronic Pain Patients.
Pain medicine (Malden, Mass.) - 1 May 2020
Fanelli Andrea, Palazzo Chiara, Balzani Eleonora, Iuvaro Alessandra, Pelotti Susi, Melotti Rita Maria
Abstract excerpt
BACKGROUND: A proper antalgic treatment is based on the use of titrated drugs to provide adequate relief and a good tolerability profile. Therapies have a variable effectiveness among subjects depending on medical and genetic conditions. CYP2D6 variations determine a different clinical response to most analgesic drugs commonly used in daily clinical practice by influencing the drugs' pharmacokinetics. This study...
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